Antenatal magnesium sulfate and intestinal morbidities in preterm infants with extremely low gestational age

BackgroundAntenatal magnesium sulfate is widely used as a tocolytic, for maternal seizures, and seizure prophylaxis in preeclampsia. Recent studies have suggested that antenatal use associated with favorable neurodevelopmental outcomes preterm infants. However, there are concerns regarding the effects of on neonates, especially gastrointestinal morbidities. This study aims to explore intestinal morbidities requiring surgery infants.MethodsThis was retrospective cohort 181 infants who were born at less than 28 weeks gestational age. Subjects categorized exposed those not sulfate.ResultsAntenatal decreased risk surgical conditions intestine (OR 0.393, 95% CI 0.170–0.905). The multivariate analysis showed duration (adjusted OR 0.766, 0.589–0.997). In <26 age subgroup, significantly 0.234, 0.060–0.922).ConclusionAntenatal appears protective effect duration-dependent manner. Association more distinct Antenatal sulfate. 0.060–0.922).